Catalog Number: RNPP-74355004
| Size: 200µl 2ml Customization | Inquiry |
|---|
| Gene ID: | PP7435_Chr4-0769 |
| Gene Name: | TFB2 |
| Gene Location: | chr4: 1305821..1307464 |
| DNA Length (bp): | 1644 |
| Protein Length (aa): | 547 |
| Gene Description: |
RNA polymerase II transcription factor B subunit 2 Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment In transcription, TFIIH has an essential role in transcription initiation When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription |
| Medium: |
YPD + 1M Sorbitol broth 30% glycerol |
| Shipping condition: | Frozen Gel Packs |
| Storage condition/Stability: |
-80℃/At least 12 months 4°C/Up to 1 week |
| Hazardous: | No |
Disclaimer
This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.
