Products

Pichia pastoris CBS 7435 THI4 Knockout Strain

Catalog Number: RNPP-74353500

Size: 200µl 2ml Customization Inquiry
Gene Information
Gene ID: PP7435_Chr3-0552
Gene Name: THI4
Gene Location: chr3: 1007305..1008342
DNA Length (bp): 1038
Protein Length (aa): 345
Gene Description: Thiamine thiazole synthase (Thiazole biosynthetic enzyme) (EC 2.4.2.60)
Involved in biosynthesis of the thiamine precursor thiazole
Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate
The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate
The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme
May have additional roles in adaptation to various stress conditions and in DNA damage tolerance
Specifications
Medium: YPD + 1M Sorbitol broth
30% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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