Products

Saccharomyces cerevisiae ATG18 Knockout Strain

Catalog Number: RNSS-4742283

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YFR021W
Gene Name: ATG18
Gene Location: Chr VI: 194812..196314
DNA Length (bp): 1503
Protein Length (aa): 500
Gene Description: Phosphoinositide binding protein
Required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (CVT) pathway
Binds PtdIns(3, 5)P2, PI3P and PI4P
WD-40 repeat containing protein and PROPPIN family member
Relocalizes from the vacuole to cytoplasm upon DNA replication stress
Mammalian homologs include: WIPI1, WIPI2, WIPI3 and WIPI4/WDR45
Mutations in human WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood (SENDA)
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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