Products

Saccharomyces cerevisiae ATG5 Knockout Strain

Catalog Number: RNSS-4746298

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YPL149W
Gene Name: ATG5
Gene Location: Chr XVI: 271310..272194
DNA Length (bp): 885
Protein Length (aa): 294
Gene Description: Conserved protein involved in autophagy and the Cvt pathway
Undergoes conjugation with Atg12p to form a complex involved in Atg8p lipidation
Atg5p-Atg12p conjugate enhances E2 activity of Atg3 by rearranging its catalytic site, also forms a complex with Atg16p
The Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation
Also involved in methionine restriction extension of chronological lifespan in an autophagy-dependent manner
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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