Products

Saccharomyces cerevisiae CSE4 Knockout Strain

Catalog Number: RNSS-4743852

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YKL049C
Gene Name: CSE4
Gene Location: Chr XI: 346075..346764
DNA Length (bp): 688
Protein Length (aa): 230
Gene Description: Centromeric histone H3-like protein
Associates with promoters, accessible chromatin, and RNAPII-bound regions
Phosphorylated Cse4p associates with centromeres
Required for kinetochore function
Ipl1p-dependent phosphorylation destabilizes defective kinetochores promoting bi-orientation
Increases association of Sgo1p with centromeric chromatin
Proteolysis regulated by multiple E3 ligases, resulting in faithful chromosome segregation
CSE4 complements mutations in the human homolog CENPA
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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