Products

Saccharomyces cerevisiae DBR1 Knockout Strain

Catalog Number: RNSS-4743733

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YKL149C
Gene Name: DBR1
Gene Location: Chr XI: 167612..168829
DNA Length (bp): 1216
Protein Length (aa): 406
Gene Description: RNA lariat debranching enzyme
Catalyzes debranching of lariat introns formed during pre-mRNA splicing
Required for efficient Ty1 transposition
Knockdown of human homolog Dbr1 rescues toxicity of RNA-binding proteins TDP-43 and FUS which are implicated in amyotrophic lateral sclerosis (ALS), suggests potential therapeutic target for ALS and related TDP-43 proteinopathies
Human homolog DBR1 can complement yeast dbr1 null mutant
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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