Catalog Number: RNSS-4745747
Size: 200µl 2ml Customization | HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 | Inquiry |
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Gene ID: | YOL021C |
Gene Name: | DIS3 |
Gene Location: | Chr XV: 282421..285426 |
DNA Length (bp): | 3004 |
Protein Length (aa): | 1002 |
Gene Description: |
Exosome core complex catalytic subunit Has both endonuclease and 3'-5' exonuclease activity Involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm Role in degradation of tRNAs Similar to E. coli RNase R and to human DIS3, which partially complements dis3-81 heat sensitivity Mutations in Dis3p analogous to human mutations implicated in multiple myeloma impair exosome function Protein abundance increases under to DNA replication stress |
Medium: |
YPD broth with G418 (200 µg/mL) 15% glycerol |
Shipping condition: | Frozen Gel Packs |
Storage condition/Stability: |
-80℃/At least 12 months 4°C/Up to 1 week |
Hazardous: | No |
Disclaimer
This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.