Products

Saccharomyces cerevisiae DIS3 Knockout Strain

Catalog Number: RNSS-4745747

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YOL021C
Gene Name: DIS3
Gene Location: Chr XV: 282421..285426
DNA Length (bp): 3004
Protein Length (aa): 1002
Gene Description: Exosome core complex catalytic subunit
Has both endonuclease and 3'-5' exonuclease activity
Involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm
Role in degradation of tRNAs
Similar to E. coli RNase R and to human DIS3, which partially complements dis3-81 heat sensitivity
Mutations in Dis3p analogous to human mutations implicated in multiple myeloma impair exosome function
Protein abundance increases under to DNA replication stress
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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