Products

Saccharomyces cerevisiae DPB11 Knockout Strain

Catalog Number: RNSS-4743384

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YJL090C
Gene Name: DPB11
Gene Location: Chr X: 262757..265051
DNA Length (bp): 2293
Protein Length (aa): 765
Gene Description: DNA replication initiation protein
Loads DNA pol epsilon onto pre-replication complexes at origins
Checkpoint sensor recruited to stalled replication forks by the checkpoint clamp complex where it activates Mec1p
Along with Rfa1p, binds to ultrafine anaphase bridges in mitotic cells and prevents accumulation of chromatin bridges by stimulating the Mec1p kinase and suppressing homologous recombination
Ortholog of human TopBP1
Forms nuclear foci upon DNA replication stress
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

Lifeasible

Copyright © Lifeasible. All rights reserved.