Products

Saccharomyces cerevisiae ESP1 Knockout Strain

Catalog Number: RNSS-4742769

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YGR098C
Gene Name: ESP1
Gene Location: Chr VII: 682566..687458
DNA Length (bp): 4891
Protein Length (aa): 1631
Gene Description: Separase/separin, a caspase-like cysteine protease
Cleaves Mcd1p/Scc1p, a mitotic cohesin complex subunit, resulting in the dissociation of cohesin from chromatin and sister chromatid separation
Cleaves meiotic-cohesin subunit Rec8p along chromosome arms in meiosis I and at centromeric sites during meiosis II
Inhibits PP2A-Cdc55p to promote mitotic exit
Inhibited by Pds1p (securin)
Relative distribution to the nucleus increases upon DNA replication stress
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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