Products

Saccharomyces cerevisiae LAS17 Knockout Strain

Catalog Number: RNSS-4745988

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YOR181W
Gene Name: LAS17
Gene Location: Chr XV: 675939..677840
DNA Length (bp): 1902
Protein Length (aa): 633
Gene Description: Actin assembly factor
C-terminal WCA domain activates Arp2/3 complex-mediated nucleation of branched actin filaments, polyproline domain nucleates actin filaments independent of Arp2/3
Mutants are defective in endocytosis, bud site selection, cytokinesis
Human homolog WAS (Wiskott-Aldrich Syndrome) implicated in severe immunodeficiency
Human WAS complements yeast null mutant, but only in presence of WIPF1, which mediates localization of WAS to cortical patches
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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