Products

Saccharomyces cerevisiae NPL4 Knockout Strain

Catalog Number: RNSS-4740405

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YBR170C
Gene Name: NPL4
Gene Location: Chr II: 576344..578086
DNA Length (bp): 1741
Protein Length (aa): 581
Gene Description: Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase
Assists Cdc48p in the dislocation of misfolded, polyubiquitinated ERAD substrates that are subsequently delivered to the proteasome for degradation
Also involved in the regulated destruction of resident ER membrane proteins, such as HMG-CoA reductase (Hmg1/2p) and cytoplasmic proteins (Fbp1p)
Role in mobilizing membrane bound transcription factors by regulated ubiquitin/proteasome-dependent processing (RUP)
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.
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