Catalog Number: RNSS-4746292
Size: 200µl 2ml Customization | HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 | Inquiry |
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Gene ID: | YPL153C |
Gene Name: | RAD53 |
Gene Location: | Chr XVI: 261727..264192 |
DNA Length (bp): | 2464 |
Protein Length (aa): | 822 |
Gene Description: |
DNA damage response kinase Signal transduction pathway component required for DNA damage and replication checkpoints, promoting cell cycle arrest and DNA repair Role in initiation of DNA replication Inhibits gene gating through NPC protein phosphorylation, to promote fork stability Activates downstream kinase Dun1p Senses mtDNA depletion and mitochondrial ROS Relocalizes to cytosol under hypoxia Contains two FHA domains Human homolog CHEK2 implicated in breast cancer complements the null |
Medium: |
YPD broth with G418 (200 µg/mL) 15% glycerol |
Shipping condition: | Frozen Gel Packs |
Storage condition/Stability: |
-80℃/At least 12 months 4°C/Up to 1 week |
Hazardous: | No |
Disclaimer
This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.