Products

Saccharomyces cerevisiae RAD53 Knockout Strain

Catalog Number: RNSS-4746292

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YPL153C
Gene Name: RAD53
Gene Location: Chr XVI: 261727..264192
DNA Length (bp): 2464
Protein Length (aa): 822
Gene Description: DNA damage response kinase
Signal transduction pathway component required for DNA damage and replication checkpoints, promoting cell cycle arrest and DNA repair
Role in initiation of DNA replication
Inhibits gene gating through NPC protein phosphorylation, to promote fork stability
Activates downstream kinase Dun1p
Senses mtDNA depletion and mitochondrial ROS
Relocalizes to cytosol under hypoxia
Contains two FHA domains
Human homolog CHEK2 implicated in breast cancer complements the null
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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