Products

Saccharomyces cerevisiae SAE2 Knockout Strain

Catalog Number: RNSS-4742453

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YGL175C
Gene Name: SAE2
Gene Location: Chr VII: 173285..174322
DNA Length (bp): 1036
Protein Length (aa): 346
Gene Description: Endonuclease required for telomere elongation
Required for telomeric 5' C-rich strand resection
Involved in ds-break repair and processing hairpin DNA structures with the MRX complex
Function requires sumoylation and phosphorylation
Exists as inactive oligomers that are transiently released into smaller active units by phosphorylation
DNA damage triggers Sae2p removal, so active Sae2p is present only transiently
Sequence and functional similarity with human CtIP/RBBP8
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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