Products

Saccharomyces cerevisiae SGS1 Knockout Strain

Catalog Number: RNSS-4744970

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YMR190C
Gene Name: SGS1
Gene Location: Chr XIII: 640915..645258
DNA Length (bp): 4342
Protein Length (aa): 1448
Gene Description: RecQ family nucleolar DNA helicase
Role in genome integrity maintenance, chromosome synapsis, meiotic joint molecule/crossover formation
Stimulates activity of Top3p
Rapidly lost in response to rapamycin in Rrd1p-dependent manner
Forms nuclear foci upon DNA replication stress
Yeast SGS1 complements mutations in human homolog BLM implicated in Bloom syndrome
Also similar to human WRN implicated in Werner syndrome
Human BLM and WRN can each complement yeast null mutant
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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