Products

Saccharomyces cerevisiae SIR2 Knockout Strain

Catalog Number: RNSS-4741256

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YDL042C
Gene Name: SIR2
Gene Location: Chr IV: 376757..378445
DNA Length (bp): 1687
Protein Length (aa): 563
Gene Description: Conserved NAD+ dependent histone deacetylase of the Sirtuin family
Deacetylation targets are primarily nuclear proteins
Required for telomere hypercluster formation in quiescent yeast cells
Involved in regulation of lifespan
Plays roles in silencing at HML, HMR, telomeres, and rDNA
Negatively regulates initiation of DNA replication
Functions as regulator of autophagy like mammalian homolog SIRT1, and also of mitophagy
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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