Products

Saccharomyces cerevisiae SIR3 Knockout Strain

Catalog Number: RNSS-4744060

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YLR442C
Gene Name: SIR3
Gene Location: Chr XII: 1019315..1022251
DNA Length (bp): 2935
Protein Length (aa): 979
Gene Description: Silencing protein
Interacts with Sir2p, Sir4p, and histone H3/H4 tails to establish transcriptionally silent chromatin
Required for spreading of silenced chromatin
Recruited to chromatin through interaction with Rap1p
C-terminus assumes variant winged helix-turn-helix (wH) fold that mediates homodimerization, which is critical for holo-SIR complex loading
Required for telomere hypercluster formation in quiescent yeast cells
Has paralog ORC1 from whole genome duplication
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

Lifeasible

Copyright © Lifeasible. All rights reserved.