Products

Saccharomyces cerevisiae SPO11 Knockout Strain

Catalog Number: RNSS-4743264

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YHL022C
Gene Name: SPO11
Gene Location: Chr VIII: 62961..64157
DNA Length (bp): 1195
Protein Length (aa): 399
Gene Description: Meiosis-specific protein required for meiotic recombination
Makes DNA double-strand breaks (DSB) during meiotic recombination, homolog pairing, and synaptonemal complex formation
Role in meiotic DSB formation involves a topo-II-like transesterase mechanism
Forms monotetrameric complex
Covalently linked to DSBs through a 5'-phosphodiester bond between a catalytic tyrosine (Y135) and the DSB 5'- end
Sequence similarity to a topo VI subunit from archaea, fission yeast rec12 and human SPO11
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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