Products

Saccharomyces cerevisiae TDP1 Knockout Strain

Catalog Number: RNSS-4740470

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YBR223C
Gene Name: TDP1
Gene Location: Chr II: 668663..670297
DNA Length (bp): 1633
Protein Length (aa): 545
Gene Description: Tyrosyl-DNA phosphodiesterase I
Hydrolyzes 3' and 5'-phosphotyrosyl bonds
Involved in the repair of DNA lesions created by topo I and topo II
Mutations in the human homolog, TDP1, result in the a neurodegenerative disease, spinocerebellar ataxia with axonal neuropathy (SCAN1)
Yeast cells and human rhabdomyosarcoma lines that overexpress TDP1 both exhibit elevated dosage chromosomal instability (dCIN)
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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