Products

Saccharomyces cerevisiae TOP2 Knockout Strain

Catalog Number: RNSS-4745380

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YNL088W
Gene Name: TOP2
Gene Location: Chr XIV: 457704..461990
DNA Length (bp): 4287
Protein Length (aa): 1428
Gene Description: Topoisomerase II
Relieves torsional strain in DNA by cleaving and re-sealing phosphodiester backbone of both positively and negatively supercoiled DNA
Cleaves complementary strands
Localizes to axial cores in meiosis
Required for replication slow zone (RSZ) breakage following Mec1p inactivation
Human homolog TOP2A implicated in cancers, and can complement yeast null mutant
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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