Products

Saccharomyces cerevisiae UBR1 Knockout Strain

Catalog Number: RNSS-4742882

Size: 200µl 2ml Customization HetDip/BY4743 HomDIp/BY4743 MATa/BY4741 MATalpha/BY4742 Inquiry
Gene Information
Gene ID: YGR184C
Gene Name: UBR1
Gene Location: Chr VII: 859901..865753
DNA Length (bp): 5851
Protein Length (aa): 1951
Gene Description: E3 Ub-ligase (N-recognin)
Recognizes and ubiquitinates N-end rule pathway substrates in complex with Rad6p
Roq1p-bound form accelerates degradation of misfolded and native ER membrane and cytosolic proteins as part of the stress-induced homeostatically regulated protein degradation (SHRED) pathway
Role in ER-associated protein degradation
Modifies Cup9p to regulate peptide transport
Mutation in human UBR1 causes Johansson-Blizzard Syndrome (JBS)
Specifications
Medium: YPD broth with G418 (200 µg/mL)
15% glycerol
Shipping condition: Frozen Gel Packs
Storage condition/Stability: -80℃/At least 12 months
4°C/Up to 1 week
Hazardous: No

Disclaimer

This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

For research use only. Not intended for any clinical use.

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