Improving Anabolism in Plant Growth

The dramatic increase in the world's population means that more food is needed to feed the global population. In contrast, factors such as frequent global climate extremes, decreasing arable land area, and soil pollution caused by the overuse of chemical fertilizers pose many challenges to agricultural production. Therefore, it is essential to provide innovative solutions to address bottlenecks in agricultural production.

Based on the urgent needs of agricultural development, Lifeasible has been building and designing new anabolic pathways in plants based on the close integration of synthetic biology and plant metabolic engineering, aiming to provide a wider range of design ideas and operational possibilities for improving plant growth and crop yield. Our in-depth research in plant anabolism, continuous design, and optimization of plant anabolic pathways have shown essential applications in the field of anabolic research in the field of agricultural research.

Fig.1. CETCH cycle. (Schwander T, et al., 2017)

Improved anabolic pathways for improved plant growth and agricultural yields

Agricultural yield is mainly affected by light energy capture efficiency, conversion of light energy to biomass, and harvest index. While light energy capture efficiency and harvest index have reached their biological limits, the conversion efficiency is currently shown to be only 20% of the theoretical maximum, so increasing plant conversion efficiency will hopefully increase agricultural yield. We have optimized and redesigned carbon metabolism through the development of anabolism and the use of new synthetic pathways for improving the conversion of light energy to biomass, effectively helping to improve plant growth.

• Development of anabolic pathways
• Optimization and redesign of carbon metabolism

Genetic engineering and plant engineering to control anabolism and improve plant growth

Genetic engineering

• To study the exact functions of genes encoding signaling molecules in the carbon metabolism pathway using RNA interference technology and to optimize and design the carbon metabolism pathway in plants.
• To explore anabolic-related genes or regulators in plants, study different candidate genes, promoters, promoter regulation, etc. In addition, we use dynamic regulation of genetic circuits to translate signals from the intra- and extracellular environment into precise control of enzyme protein expression using the interaction of small molecules with transcription factors and the interaction of transcription factors with specific DNA regions to ensure that cells always regulate metabolic activities to adapt to environmental changes and improve plant growth.

Plant engineering

We use modern engineering principles of biological systems based on modular genetic components and mathematical models to guide the design and characterization of quantitative functions of individual components to assemble and construct synthetic biological systems that help improve plant growth through anabolism.

• Develop the Calvin Cycle (CBBC) and seek more efficient methods for CO₂ fixation.
• Engineering chloroplast photorespiratory bypasses to reduce photorespiratory CO₂ losses can effectively promote plant growth.

Our advantages and features

Lifeasible is committed to providing innovative solutions to increase agricultural productivity. We achieve higher crop yields by maximizing plant structure and photosynthetic utilization with our advanced technology platform and experienced team of expert technicians; we aim to provide the highest level of customer satisfaction. If you are interested in us, please feel free to contact us.