Development of RNA Pesticides

RNA pesticides, using the principle of RNA interference, cause biological stagnation or death of pests by suppressing the expression of critical functional genes in the organism. This achieves pest and disease control. New technological revolution, RNA pesticides, particularly for those stubborn, highly resistant pests and diseases. RNA pesticides are plant protection solutions directly from the gene mechanism of action. The development of RNA pesticides is a major trend in global green agriculture.

Lifeasible focuses on pesticide development. We have built a library of key target genes for more than 100 pests and diseases and established a series of RNA pesticide development technologies and industrialization platforms from R&D to production. The RNA pesticides we developed have the advantages of controlling pests and diseases without affecting crops' genetic expression and being green and pollution-free, providing a new solution for sustainable agricultural development.

Effective application of RNA interference technology in plant protection

We provide RNA interference technology, which can cause developmental arrest or death of harmful organisms by blocking gene expression through specific degradation of intracellular homologous mRNA triggered by endogenous or exogenous double-stranded RNA, thereby inhibiting essential functions of the organism. We offer RNA interference technology, which has been widely used in breeding and plays a crucial role in plant protection. We use RNA interference technology to kill crop pests, pathogens, and weeds, providing an effective solution for sustainable agricultural development.

Technical aspects of RNA pesticide development

RNA pesticide is a high-tech product that combines bioinformatics, synthetic biology and nanomaterials technologies. The main technical aspects are as follows.

• Screening for target genes.
• Double-stranded (ds) RNA design and construction.
• Expression technology for dsRNA.
• Efficient, low-cost, and large-scale dsRNA biosynthesis and preparation technology.
• Preparation of functional nanomaterials.
• Creation of technology for nano-formulations, etc.

Advantages of RNA pesticides in pest control

• High specificity and positive effect. It is highly targeted to specific genes, has a cascade amplification waterfall effect, and can act on multiple targets to improve killing efficiency.
• Not susceptible to resistance. When acting, it is cleaved into multiple siRNAs, one of which binds to the target gene once to stimulate the silencing of the target gene. The probability of resistance through gene mutation or off-target is extremely low.
• Non-toxic, harmless, and residue-free. Double-stranded (ds) RNA is designed to act only on specific pests and is non-toxic to humans and other non-targets, with a clean production process and degradation within 72 h in soil and water.
• Low R&D costs. Custom development based on specific genes, no need for mass matching and screening.

Advantages of our services

Lifeasible specializes in biopesticide development, and we have extensive knowledge of pesticide and insecticide protein development. Our professional and efficient service can help our customers to solve various challenges in the progress of their projects. If you are interested in us, please feel free to contact us.