Toxicological Analysis of Herbal Medicines

The complexity of the herbal species and their different qualities make for a wide range of toxic substances, including inorganic and organic toxic substances. The toxicological effects of herbs are also very diverse, and reactions can be seen in many body systems, including the cardiovascular, nervous, respiratory, digestive, hematological, and reproductive systems. The mechanisms by which toxic effects occur include the transport of toxic substances from the site of exposure to the target site, the reaction of the end toxicant with the target molecule, cellular dysfunction, and the resulting toxicity and toxicity due to repair and restoration disorders. Lifeasible offers a systemic toxicology service for herbal medicines. We help you to explore the intrinsic link between systemic exposure and toxicity under toxicity testing conditions, comparing systemic exposure in animals and humans to explain the value of toxicology data. We can also support the safety evaluation of drugs through toxicokinetic studies in different toxicity tests and the results of varying toxicity studies.

Toxicity analysis of herbal medicines

We offer simple and rapid preliminary screening and analysis of herbal toxicity through computerized predictive and virtual screening techniques that integrate chemistry, molecular biology, toxicology, statistics, and computer science. We build mathematical and computer models to investigate the toxic compounds, side effects, and mechanisms of toxicity of herbal medicines.

Toxicokinetics of herbal medicines

We provide a toxicokinetic analysis service for herbal medicines, which aim is to reveal the intrinsic link between the systemic exposure achieved and the onset of toxicity under toxicity testing conditions, to compare the value of systemic exposure with that of humans in interpreting toxicological data, and to support the design of protocols for herbal toxicity studies.

The complex composition of herbal medicines, the large number of unknown components, the inadequate knowledge of the active and/or toxic components, and the uncertainty of the correlation between in vivo exposure and toxicity of the components lead to the unique nature of the study and management of samples for toxicological studies of new herbal medicines. Lifeasible's systemic toxicology service includes the analysis of the general toxicity, specific toxicity, and mechanism of toxicity to target organs of the drug. Please feel free to contact us to identify the target tissues or cells of the drug, determine the mechanism of toxicity, determine the dose range of toxicity, and understand the toxic effects of the herb.

• Toxicity Analysis of Herbal Medicines
• Toxicokinetics of Herbal Medicines