Lifeasible is dedicated to applying new technologies in plant protection and provides research services to help RNA interference technology be applied to various aspects of plant protection.
Plant protection has always been a focus in agricultural production. Traditional chemical agrochemical-based plant protection can pollute the soil and water and cause damage to other non-target organisms. RNA interference, as a naturally occurring biological process, is used for innovative plant disease control. RNA-based technologies have the potential to represent the next generation of crop protection strategies to reduce the use of harmful agrochemicals. RNA interference can be applied to several aspects of plant protection, including pathogen control, virus control, weed control, pest control, and adaptation to abiotic stress environments. Exploring the mechanism of action of RNA interference in plants and other organisms can help develop comprehensive plant protection applications using RNA interference.
Fig. 1 RNA interference pathways in plants (Rosa et al., 2018).
Lifeasible fuels the application of RNA interference in plant protection and provides services to help develop plant protection solutions with RNA interference. We fuel the application of RNA interference in multiple aspects of plant protection. In plant protection by RNA interference, we detail the various directions we help to explore RNA interference in various plant protection applications, including the use of RNA interference to control pests, pathogens, weeds, and viruses and to enhance abiotic stress resistance in plants. And we offer specific services based on RNA interference's design and application process.
Identification and validation of sRNAs
We provide to identify sRNAs from plants, pests, fungi, and viruses with plant protective effects. We identify sRNAs based on genomic information and sRNA sequencing information. We also provide services to validate sRNAs by methods such as qRT-PCR.
Synthesis and modification of sRNAs
We offer services to edit plant genes to produce shRNAs or dsRNAs for host-induced gene silencing (HIGS)-based plant protection. We offer the synthesis of spray-induced gene silencing (SIGS)-based sRNAs by various in vitro and in vivo synthesis methods.
We provide services to deliver sRNAs to organisms with RNA interference mechanisms, including plants, pests, and fungi. We help overcome the challenges of sRNA delivery, and we develop sRNA delivery methods from both abiotic and biotic delivery directions.
Safety assessment of RNA interference
Assessing the safety of RNA interference is indispensable in developing RNA interference to protect plants. For transgenic-based HIGS, the need for safety assessment is even greater. We help assess the safety of RNA interference applied in plant protection. We offer to evaluate its safety at molecular, environmental, and food levels.
One-stop service
We provide a one-stop service for RNA interference in plant protection. Our services cover the whole process of RNA interference, including sRNA identification, validation, synthesis, modification, delivery, and safety assessment.
Customized solutions
We offer customized services based on our clients' specific development needs for RNA interference in plant protection. We first communicate to know the customer's needs and then customize the RNA interference development program. We then implement the program after receiving the customer's confirmation.
Expertise in RNA interference and plant protection
We have professional RNA interference and plant protection researchers. They master professional RNA interference and plant protection knowledge. They work closely with our bioinformatics and gene editing experts to efficiently complete the service.
Lifeasible provides a one-stop shop for RNA interference in plant protection applications, and we provide one-on-one service design. With our expertise in RNA interference and plant protection, we are your trusted partner in developing plant protection applications using RNA interference. Please feel free to contact us for customized plant protection services based on RNA interference.
References
Lifeasible has established a one-stop service platform for plants. In addition to obtaining customized solutions for plant genetic engineering, customers can also conduct follow-up analysis and research on plants through our analysis platform. The analytical services we provide include but are not limited to the following:
