The unfolded protein response (UPR) is an intracellular signaling mechanism activated by endoplasmic reticulum (ER) stress designed to restore ER function. ER stress leads to the accumulation of folded proteins in the ER lumen. In addition, the UPR originates from the ER, where it overcomes the ER stress, restores the ER homeostasis, and leads to the ER chaperones and foldases synthesis to attenuate the ER stress. These ER chaperones and foldases are BiP, protein disulfide isomerase, glucose-regulated protein, peptidyl-prolyl isomerase or immunophilins, calnexin, and calreticulin.
Lifeasible is a credible provider of comprehensive, high-quality services for plant science. We provide an advanced and professional platform for the analysis of UPR in response to ER stress according to customer needs. We hope to partner with you to explore new frontiers in ER stress response and accelerate your discovery.
Fig.1. Overview of the pathway for UPR signaling.
NAC-Mediated Pathway in Unfolded Protein Response
With years of experience in biological services, our advanced platforms can help our clients solve various difficulties in research of ER stress response. Lifeasible provides our clients with direct access to our experts and responses to their questions. If you are interested in our services or have any questions, please feel free to contact us or make an online inquiry.
Lifeasible has established a one-stop service platform for plants. In addition to obtaining customized solutions for plant genetic engineering, customers can also conduct follow-up analysis and research on plants through our analysis platform. The analytical services we provide include but are not limited to the following: