Analysis of Active Ingredients in Herbal Medicines
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Herbal medicine exerts a holistic regulatory effect on the body through a multi-component, multi-targeted network. Herbal monomers are the active ingredients in herbal medicines, which have a variety of medicinal properties such as antioxidant, anticancer and antibacterial effects, and are an essential source for developing new drugs. Nearly 200 modern drugs are derived directly or indirectly from herbs.
Lifeasible's strategy of activity-directed isolation or post-isolation activity testing on a case-by-case basis establishes high-throughput screening techniques to help you obtain single compounds with novel structures or biological activity. We can use these as lead compounds for biotransformation, structural modification, conformational studies, etc. In addition, we have established methods for the discovery of active substance clusters appropriate to the action characteristics of herbal medicines, using the overall action of herbal medicines as an entry point to help you with active ingredient/cluster/group screening, herbal compound splitting/recombination studies, active ingredient/component discovery, etc.
We use high throughput screening as the basis for molecular and cellular methods, microplates as the vehicle for experiments, an automated operating system to perform the experiments, sensitive and fast instruments to collect the data, and a computer to analyze and process the data obtained. Thousands or tens of thousands of samples are tested simultaneously, and a corresponding database supports the entire system.
We use modern technology to elucidate the material basis of herbs, and is an essential tool in your research to improve the efficacy and stabilize the quality of herbal medicines. We can help you to identify the chemical groups that play a therapeutic role in herbal medicine or to clarify the material basis of herbal medicine's efficacy.
We are working on the construction of pharmacodynamic component groups through the screening and identification of pharmacodynamic component groups, which can simplify the complexity of multi-component herbal medicines. It is characterized by a clear substance basis, a clear mechanism of action, and a high degree of controllability.
We apply traditional drug use thinking, modern drug design principles, and other relevant methods of modern drug discovery to the design of innovative herbal medicines to help you obtain lead compounds that are consistent with the characteristics of herbal medicine (multi-component, multi-target, multi-pathway).
Please feel free to contact Lifeasible; we can meet your different development needs.
For research or industrial raw materials, not for personal medical use!
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