Mushrooms have been used as food and medicine since ancient times, and their fruiting bodies are an excellent source of therapeutic compounds. Mushrooms and their extracts contain a large number of bioactive components called secondary metabolites, such as the polysaccharide β-glucan, polysaccharide-protein complexes, etc. They have huge therapeutic applications in human health because of their various properties such as antidepressant, antiviral, anti-tumor, immunomodulatory, hypocholesterolemic, anti-inflammatory, antioxidant, etc. Mushrooms could hold the potential for the pharmaceutical industry to treat various diseases with fewer side effects compared to current medications.
Lifeasible provides one-stop preclinical research services for the development of new drugs based on mushroom active substances. We can extract, separate and identify the active substances in mushrooms, carry out activity evaluation and mechanism research, and study the drug development of mushroom active substances in various diseases.
Our Services
Lifeasible is committed to developing the potential of mushrooms in the pharmaceutical field and providing professional solutions for preclinical research on the development of new drugs based on mushroom active substances. Mushrooms have a variety of pharmacological activities, and different new drugs can be developed for different activities. Therefore, we will conduct a comprehensive activity screening of mushroom extracts in combination with computer-aided drug design, and then select appropriate models for pharmacological and efficacy evaluation based on the activity results to determine the targets and mechanisms of mushroom active substances. You can also contact us to customize preclinical-related experiments according to your experimental requirements. Our preclinical research services on new drug development based on mushroom-active substances includes but are not limited to the following:
Service Process
Discovery and screening of mushroom active substance
- Extraction
- Separation
- Structure identification
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Computer-aided drug design
- Molecular docking
- Drug-target interaction simulation
- Calculation of affinity
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Activities test
- Preliminary activity assessment
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Pharmacological and pharmacodynamic research
- In vitro model construction
- In vivo model construction
- Mechanism study
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Advantages of Our Services
- Rich and professional drug discovery and development experience in the research and development of mushroom-active compounds.
- Well-established preclinical laboratories and facilities.
- Our computer-aided drug design platform is equipped with high-performance computing clusters, drug design software, and computational chemistry software, such as Schrödinger, MOE, OpenEye, and other professional drug design software, which can ensure long-term, stable, and high-speed virtual drug screening and lead compounds design and optimization.
- We have in vivo and in vitro evaluation models for new drug research for various diseases, supporting pharmacological efficacy and drug safety evaluation research.
- We have accumulated rich experience in the establishment of disease models, pharmacodynamic evaluation and screening, etc., and can provide customers with one-stop preclinical research services in different disease fields.
Contact Us
Lifeasible is committed to exploring the maximum potential of mushrooms in medicinal applications. We are trying to develop traditional or new medicines based on mushroom bioactive substances. If you are interested in our services, please contact us as soon as possible for a detailed description of our services.
Reference
- Chaturvedi, V.K.; et al. Medicinal mushroom: boon for therapeutic applications. 3 Biotech. 2018, 8(8): 1-20.
For research use only, not for clinical use.
